What is Bone Marrow Transplant?
- Bone marrow transplant is a medical procedure that replaces healthy blood-forming cells for damaged or diseased stem cells. Healthy stem cells are isolated from a donor or patient using a catheter, filtered, and then transfused into the patient.
- Stem cells can be obtained from bone marrow, the umbilical cord, or peripheral blood cells (circulating blood stem cells).
What are the diseases for which it can be effective?
- Malignant disorders
- Leukemia (Blood or Bone marrow cancer)
- Lymphomas (Cancer of the lymphatic system)
- Multiple Myeloma (Cancer of plasma cells)
- Benign disorders
- Bone marrow failure-Aplastic Anemia (A condition in which the producing enough new blood cells)
- Storage disorders
- Multiple Myeloma (Cancer of plasma cells)
- Thalassemia, Sickle cell anemia
Types of Stem Cells Transplant:
- Autologous: Stem cells are extracted from the patient’s own peripheral blood after mobilisation, in this type of transplant.
- Allogenic: Someone who is the same type (HLA Matched) as the patient. It could be a sibling, parent, or a genetic match(Matched unrelated donor(MUD).
- Umbilical Cord Transplant: Stem cells from a newborn baby’s umbilical cord are used.
Donor-patient matching:
- The matching procedure requires typing the Human Leukocyte Antigen tissue (HLA). There are HLA antigens in the human body, and the greater the number of matching antigens, the greater the chance of a successful transplant.
- The ideal donor is the patient’s sibling. Siblings have a one in four chance of matching for bone
At MGM Cancer Institute, we use state-of-the-art technology, with the expertise of top doctors and healthcare professionals to perform autologous and allogeneic bone marrow transplants. Our experienced team of hematologists, oncologists, and transplant experts use a comprehensive and individualized approach to ensure successful outcomes.
Fact check
6 Weeks
After donation, bone marrow replaces itself within four to six weeks.
Side effects of Bone Marrow Transplant
Bone marrow transplant can cause a variety of side effects such as fatigue, nausea, vomiting, and hair loss. Our team closely monitors patients to manage these symptoms and ensure a smooth recovery process.
A Positive note for preparation
Bone marrow transplant is a complex medical procedure that requires thorough preparation. Our team provides patients with pre-transplant counseling and support to ensure they are well-informed and ready for the procedure.
Steps involved in a bone marrow transplant
Preparation : Before the transplant, the patient undergoes chemotherapy and/or radiation therapy to destroy the existing bone marrow and make room for the new cells.
Collection : The healthy stem cells are collected from either the patient’s own body (autologous transplant) or a donor (allogeneic transplant) using a procedure called apheresis. In some cases, the stem cells may be taken from the bone marrow directly.
Transplantation : The new stem cells are infused into the patient’s bloodstream through an IV. The cells travel to the bone marrow, where they begin to grow and produce new blood cells.
Recovery : After the transplant, you will be closely monitored for complications and side effects, such as infections, bleeding, and graft-versus-host disease (GVHD).
Emotional and Mental needs
We understand that a bone marrow transplant can be emotionally and mentally challenging. Our team provides compassionate care and support to help patients and their families navigate this journey.
What Can I do to help myself
Stay hydrated by drinking plenty of fluids.
Eat a healthy, balanced diet to provide your body with the nutrients it needs to heal.
Don’t hesitate to ask for help from family, friends, or support groups.
Attend all follow-up appointments with your healthcare team to monitor your progress and address any concerns.
After Treatment | After Care
After bone marrow transplant, patients require long-term follow-up care and monitoring to ensure their continued well-being. Our team provides comprehensive aftercare services and support to help patients live healthy and fulfilling lives.
Follow-up care
The patient will need to take medications to prevent GVHD (Graft Vs. Host Disease) and other complications, and will require regular follow-up visits with their healthcare team to monitor their progress and address any issues that arise
Our Care Team
Dr. M. Deenadayalan
HOD and Clinical Lead
Paediatric Haematology, Oncology, Blood and Marrow Transplantation
Dr. G. Vimal Kumar
Senior Consultant
Paediatric Haematology, Oncology, Blood and Marrow Transplantation
Dr. Rishab Bharadwaj
Consultant
Paediatric Haematology, Oncology, Blood and Marrow Transplantation
Get a Screening/Second Opinion from us
If you or a loved one is considering a bone marrow transplant , we encourage you to reach out to our team for consultation and expert advice. Our team of experts will provide personalized recommendations and support every step of the way.
FAQ
Bone marrow procedure and care plan
A bone marrow or stem cell transplant saves lives by replacing damaged bone marrow with healthy stem cells, restoring normal blood cell production and helping the body fight life-threatening diseases.
A bone marrow transplant works by replacing diseased bone marrow with healthy stem cells that restore normal blood cell production and strengthen the immune system.
Recovery after a bone marrow transplant typically takes 3 to 6 months for initial healing, while full immune system recovery may take up to one year or longer, depending on the transplant type and patient health.
Common bone marrow transplant side effects include infections, fatigue, nausea, hair loss, and graft-versus-host disease (GVHD). With proper monitoring and post-transplant care, most risks can be effectively managed.
The main types of bone marrow transplant include autologous transplant (patient’s own stem cells), allogeneic transplant (donor stem cells), and haploidentical transplant (partial donor match).
A bone marrow transplant may be required for patients with leukemia, lymphoma, multiple myeloma, aplastic anemia, thalassemia, sickle cell disease, and other serious blood or immune system disorders.
Tales from
Our Healthcaring Journey
Rose Day is a heartfelt celebration of the strength, courage, and resilience of cancer survivors. This video is a tribute to their inspiring journeys, a reminder that hope can bloom even in the toughest of times. With the unwavering support of families, friends, and caregivers, these individuals shine as symbols of perseverance and triumph. At MGM Cancer Institute, we believe in fostering hope and solidarity as we walk together on the path toward healing. Join us in honoring their stories and advocating for a brighter, cancer-free future.
| Bone Marrow Transplant
In this heart-touching testimony, a mother shares the incredible journey of her son, born after 15 years of hope and prayers, only to be diagnosed with thalassemia. Facing years of fear and uncertainty as he endured countless blood transfusions, they finally found hope in Dr. Deenadayalan and his exceptional team at MGM Cancer Institute. With their unwavering support, they cured the family’s fears first, and then their son’s illness through a successful bone marrow transplant. Today, he is healthy and thriving, living the life they once feared he might never have. This is a story of resilience, faith, and the life-changing power of modern medicine.
Dr M Deenadayalan | Bone Marrow Transplant
When you have cancer, or care about someone who does, “cure” may be the word you want to hear more than any other. It’s also a word most doctors won’t say.
There’s no cure for it, but there are treatments that may be able to cure some people of some cancers. When you understand the difference, it makes all the difference.
Dr. M A Raja, Senior Consultant Medical Oncology, Director of Oncology Services at MGM Healthcare, talks about how curing cancer is equals to treating 100 diseases. This is possible when diagnosed at a early.
Cure for each type of cancer varies from medical treatment, surgery to radiation. There are certain cancers which can be controlled & the patient can have a quality life.
Dr MA Raja | Medical oncology, BMT
Blood Cancer
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